Publications/IP/Presentations

Publications:

  • Google Scholar

    19. Wang R, Cao, S, …, Wilson DS, Hubbell JA, Nagler CR. “Treatment of peanut allergy and colitis in mice via the intestinal release of butyrate from polymeric micelles”, Nat. Biomed. Eng 7, 38–55 (2023).

    18. Gray LT, Raczy MM, Briquez PS, Marchell TM, Alpar AT, Wallace RP, Volpatti LR, Sasso MS, Cao S, Nguyen M, Mansurov A, Budina E, Watkins EA, Solanki A, Mitrousis N, Reda JW, Yu SS, Tremain AC, Wang R, Nicolaescu V, Furlong K, Dvorkin S, Manicassamy B, Randall G, Wilson DS, Kwissa M, Swartz MA, Hubbell JA., “Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant”, Biomaterials, 278, (2021).

    17. Maulloo CD, Cao S, Watkins EA, Raczy MM, Solanki AS, Nguyen M, Reda JW, Shim HN, Wilson DS, Swartz MA, Hubbell JA, “Lymph Node-Targeted Synthetically Glycosylated Antigen Leads to Antigen-Specific Immunological Tolerance”, Frontiers in Immunology, 12, (2021).

    16.     M. Damo, D.S. Wilson*, E.A. Watkins, J.A. Hubbell, “Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8 T Cell Tolerance Development”, Frontiers in Immunology, 12, 534, (2021).* Authors contributed equally to this work

    15. Card C, Wilson DS, Hirosue S, Rincon-Restrepo M, de Titta A, Güç E, Martin C, Bain O, Swartz MA, Kilarski WW., “Adjuvant-free immunization with infective filarial larvae as lymphatic homing antigen carriers”, Sci Rep, 10, (2020).

14.     D.S. Wilson, M. Damo, S. Hirosue, M.M. Raczy, K. Brunggel, G. Diaceri, X. Quaglia-Thermes, J.A. Hubbell, “Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes”, Nature Biomed. Eng., 3, 10, 817-829, (2019).  Highlighted in Nature Biomed. Eng., “News & Views:  Antigen-specific immune tolerance in the liver”, 3, 763-765 (2019).

13.     D. S. Wilson, S. Hirosue, M.M. Raczy, L. Bonilla-Ramirez, L. Jeanbart, J. Franetich, M. Kwissa, M. A. S. Broggi, G. Diaceri, X. Quaglia-Thermes, D. Mazier, M. Swartz, and J. A. Hubbell, “Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity”, Nature Materials, 18, 175, (2019).  Highlighted in Nature Materials, “News & Views:  Next-generation malaria vaccines”, 18, 94-96, (2019).

12.      S.L. Hyzy, I. Kajan, D.S. Wilson, K.A. Lawrence, D. Mason, J.K. Williams, X. R. Olivares-Navarrete, D.J. Cohen, Z. Swartz, B.D. Boyan, “Inhibition of angiogenesis impairs bone healing in an in vivo murine rapid resynostosis model”, J. Biomed Mater Res A. 105, 2742, (2017).

11.     N. Murthy, D.S. Wilson, J.C. Sy, S.N. Aqida, (2015) “Biodegradation of Polymers”, (G. Smithers Ed.) Reference Module in Materials Science and Materials Engineering, Amsterdam, NL:  Elsevier.

10.      M. Damo, D.S. Wilson, E. Simeoni, J.A. Hubbell, “TLR-3 stimulation improves immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma”, Sci. Rep. 5, 17622, (2015).

9.       C.D. Herman*, D.S. Wilson*, K.A. Lawrence, X. Ning, R. Olivares-Navarrete, J.K. Williams, R.E. Guldberg, N. Murthy, Z. Swartz, B.D. Boyan, “Rapidly polymerizing injectable click hydrogel therapy to delay bone growth in a murine resynostosis model”, Biomaterials, 35, 9698, (2014).  * Authors contributed equally to this work

8.       R.E. Whitmire, D.S. Wilson, A. Singh, M.E. Levenston, N. Murthy, A.J. Garcia, “Self-assembling nanoparticles for intra-articular delivery of anti-inflammatory proteins”, Biomaterials, 30, 7665, (2012).

7.       D.S. Wilson, G. Dalmasso, L. Wang, S. Sitaraman, D. Merlin, N. Murthy., “Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA target inflammation and inhibit gene expression in the intestines”, Nature Materials, 9, 923, (2010).

6.      H. Laroui, D.S. Wilson, G. Dalmasso, K. Salaita, N. Murthy, S. Sitaraman, D. Merlin, “Nanomedicine in GI”, Am. J. Physiol. Gastro. Liver Physiol. 300, G371, (2010).

5.      M.C. Gongora, H.E. Lob, U. Landmesser, T.J. Guzik, W.D. Martin, K. Ozumi, S.M. Wall, D.S. Wilson, N. Murthy, M. Gravanis, T. Fukai, D.G. Harrison, “Loss of extracellular superoxide dismutase leads to acute lung damage in the presence of ambient air: a potential mechanism underlying adult respiratory distress syndrome”, Am. J. Pathol., 173, 915, (2008).

4.       D.S. Wilson, L.L Lee, “Chemical Potentials and Phase Equilibria of Lennard-Jones Mixtures: A Self-consistent Integral Equation Approach”, J. Chem. Physics, 123, 44512, (2005).

3.      D.S. Wilson, L.L. Lee, “Molecular Recognition and Adsorption Equilibria in Starburst Dendrimers:  Gas Structure and Sensing via Molecular Theory”, Fluid Phase Equilibria, 228-229, 197, (2005).

2.      G. Pellicane, C. Caccamo, D.S. Wilson, L.L. Lee, “Replica Ornstein-Zernike Self-Consistent Theory for Mixtures in Random Pores”, Phys. Rev. E, 69, 61202, (2004).

1. J.H. McFall, D.S. Wilson, L.L Lee, “Accurate Correlation of the Second Virial Coefficients of Some 40 Chemicals Based on an Anisotropic Square-Well Potential”, Ind. Eng. Chem. Res., 41, 1107, (2002).

Intellectual Property :

  • 2017, WO2017058996, “Polymer-conjugate vaccines”

  • 2015, WO2015140648, “Glycotargeting therapeutics”  

  • 2012, WO2012126005, “Polymer hydrogels for in vivo applications and methods for using and  preparing the same”

  • 2012, WO2012142292, “Bifunctionalized polymer microparticles for bitherapeutic delivery”.

  • 2012, WO2012138694, “Compositions comprising saccharide binding moieties and methods for targeted therapy”

Select Conference Presentations:

1.       D.S. Wilson, S. Hirosue, M.R. Raczy, M.A. Swartz, J.A. Hubbell, “Glyco-Adjuvant Vaccine for Enhanced Cellular and Humoral Immunity”, Bioengineering & Translational Medicine Conference, 2018.

2.       D.S. Wilson, S. Hirosue, M.R. Raczy, M.A. Swartz, J.A. Hubbell, “Glyco-adjuvant Vaccines for Enhanced Cellular and Humoral Immunity”, Society for Biomaterials, 2018.

3.       D.S. Wilson, S. Hirosue, M.R. Raczy, M.A. Swartz, J.A. Hubbell, “Vaccination with poly(Mannose)-antigen Conjugates Combined with a Novel TLR7 Agonist Enhances Cellular Immune Response”, Biomedical Engineering Society, 2016.

4.       D.S. Wilson, S. Hirosue, M.R. Raczy, M.A. Swartz, J.A. Hubbell, “Vaccination with Poly(mannose)-antigen Conjugates Combined with a Novel TLR7 Agonist Enhances Cellular Immune Response”, Fusion Drug Delivery Conference, 2015. 

5.       D.S. Wilson, G. Dalmasso, D. Merlin, N. Murthy, “Orally Delivered Thioketal-nanoparticles Loaded with siRNA Inhibit Gene Expression at Sights of Intestinal Inflammation”, Society for Biomaterials, 2011.

6.       D.S. Wilson, G. Dalmasso, D. Merlin, N. Murthy, “Orally Delivered Thioketal-nanoparticles Loaded with siRNA Target Reactive Oxygen Species and Inhibit Gene Expression in the Intestines”, Biomedical Engineering Society, 2010.

7.       D.S. Wilson, G. Dalmasso, D. Merlin, N. Murthy, “A Reactive Oxygen Species Sensitive Drug Delivery Vehicle for The Oral Delivery of siRNA”, Controlled Release Society Annual Meeting, 2010. Award for Outstanding Oral Delivery Paper.

8.       D.S. Wilson, G. Dalmasso, D. Merlin, N. Murthy, “Superoxide-sensitive Delivery Vehicle for the treatment of intestinal inflammation”, American Chemical Society, 2008.